Cookie clicker permanent upgrade slots

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For #1, I am at the point in the game where I can afford kitten strategists fairly quickly, and it's the highest kitten upgrade in the game (my prestige level is about 100 trillion). I don't know if I am using the right upgrade for numbers 1 and 5.

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Safety patrols (will switch to fortune #020 when I get it).

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I have been using an ascension guide on Steam to know what heavenly upgrades I should buy and what permaslots to use (among other things), but I don't know if the permaslots suggested are the best for the point I'm at. Other versions are knockoffs and not to be discussed here. The official mobile version for android was uploaded by Dashnet. Only posts related to Cookie Clicker are allowed Questions that are answered elsewhere may be deleted. The answers to most questions about the game can usually be found in one of these three locations. Please search the subreddit, the wiki and the subreddit wiki before asking any questions about the game. If you need help, explain your problem in detail and post screenshots of your stats. Please report spam and posts that break the subreddit or Reddit rules. It was released on August 8th, 2013 by /u/Orteil. r/cookieclicker is here to help you make more cookies.

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